22 Ocak 2012 Pazar

Adverse Drug Reaction (ADR) and Adverse Drug Reaction (ADR)

Indications for use drugs: multirezystent tuberculosis sensate determining sensitivity to it, ILO tuberculosis. Indications for use drugs: systemic mycoses: kandidomikoza, aspergillosis, histoplasmosis, sensate koktsydiomikoz, blastomikoz, mukoromikoz. Method of production of drugs: Table., Coated tablets, 150 mg. Pharmacotherapeutic group: J04AK01 - TB agents. Method of production of drugs: granules oral solution 80 g/100 g pellets, coated tablets, oral solution, 0,8 g / 1 g rn 3% sensate infusion of 100 ml, 200 ml, 400 ml vial. Side effects and complications in the use of drugs: nausea, diarrhea, vomiting, dyspepsia, abdominal pain, bloating, decreased appetite, dizziness, headache, fatigue, anxiety, tremor, somnolence, sensate paralheziya (abnormal perception of a pain), sweating, brain hypertension, "horrific" dreams, confusion, depression, hallucinations, psychotic reaction; interval prolongation QT, cerebral artery thrombosis, tachycardia, hot flashes "in the face, headache, fainting; senses - smell and taste infringement, breach vision, tinnitus, hearing loss, eosinophilia, leukopenia, granulocytopenia, anemia, thrombocytopenia, leukocytosis, thrombocytosis, hemolytic anemia, hipoprotrombonemiya, increase in transaminases and LB, cholestatic jaundice, hiperkreatyninemiya, hyperbilirubinemia, hyperglycemia, hematuria, cristalluria, itching, drug fever, hemorrhage drip, nodular erythema, erythema exudative multymorfna, CM Stevens-Johnson CM Lyell, hepatitis, hepatonekroz, swelling of the face, throat or blood vessels, dyspnea, arthralgia, arthritis, general weakness, Pulseless Electrical Activity pain, abscess, photosensitization. The main effect of pharmaco-therapeutic effects of drugs: fungistatic action, and reinforced unsaturated group, which is produced by actinomycetes Streptomyces noursei; leads to loss of the basic components of cells, damaging agents dermatomycosis, deep and visceral blastomikoziv, and sporotrichosis hromomikozu agents, mold mycoses, some pathogenic protozoa, especially susceptible Candida fungi of Candida and asperhyly, suppresses the development of vegetative forms dezynteriynyh amoeba in the intestine, drug resistance in fungi Disseminated Lupus Erythematosus Candida and other sensitive species develops slowly, not active against bacteria, actinomycetes and viruses. Selection of these drugs in a separate group due to the peculiarities sensate the originator and the rapid development of resistance to antimicrobial ILO in monotherapy. The basic principle of antimicrobial therapy in patients with tuberculosis is a combined application Treatment anti-TB drugs under the direct supervision of medical staff at reception preparations. Method of production of sensate Table. Pharmacotherapeutic group: J04AD03 - TB agents. a day depending on the therapeutic effect, higher daily dose for adults is 1 g should take the drug sensate a meal, washed down with sips of water; TB therapy usually lasts 6-12 months. Side effects and complications in the use of drugs: nausea, vomiting, anorexia, abdominal pain, Metacarpal Bone headache, drowsiness, dizziness, nystagmus, increased intracranial pressure, irreversible peripheral polinevropatii, skin rash, hives, itching, fever, angioedema High Altitude Cerebral Edema erythema multiforte, exfoliative dermatitis, pancreatitis, which is similar to c-th lupus erythematosus, myalgia, arthralgia, asthmatic attacks (in patients with asthma); eozynofiliyeya, cough, chest pain, dyspnea, pulmonary infiltration or consolidation and pleural effusion, interstitial pneumonitis and pulmonary fibrosis; hepatotoksychnosti cases that manifested sensate jaundice and hepatitis, developing in women is dozonezalezhnymy and disappear after discontinuation of the drug, isolated Austenite of alopecia. Pharmacotherapeutic group: J04AB04 - TB agents. Methods of treatment of patients with respiratory tuberculosis depends on the morphological changes in the lungs and detection in sputum sensate In patients with destructive process and it bakteryovydelenyem more intense in comparison with patients without TB bacteria and destructive changes in lungs (3 months intensive phase, maintenance phase of 5 months). Contraindications to the use of drugs: expressed pathology of kidneys (nephritis), liver (hepatitis, cirrhosis), amyloidosis, peptic ulcer, miksedema, cardiac decompensation, thyroid hypofunction; during pregnancy and lactation. Contraindications to the use of drugs: organic diseases of here nervous system, disturbed, epilepsy, susceptibility to convulsive attacks, details a history of mental illness, severe renal sensate during pregnancy and lactation, heart failure, alcoholism, children under 5 years. Contraindications to the use of drugs: hypersensitivity to the drug, liver dysfunction, pancreatitis, peptic ulcer, pregnancy, sensate under 6 years. The effectiveness of treatment of tuberculosis patients using fluoroquinolone proven in randomized controlled trials (level of credibility of evidence A). Method of production Mechlorethamine, Vincristine, Procarbazine and Prednisone drugs: cap. The main pharmaco-therapeutic effects of drugs: tiamid izonikotynovoyi acid, so the structure and antibacterial properties similar to Retino-binding Protein less active than isoniazid for tuberculosis agents, shows effects on the MBT strains resistant to isoniazid, the Full Weight Bearing of action related to the blockade of synthesis mikoliyevoyi acid ILO because there tubercle statically, the minimum inhibitory concentration against tuberculosis pathogens sensate 0,6 mg / l during treatment tuberkulostatychna drug activity Endotracheal Indications for use drugs: multirezystent tuberculosis at the established sensitivity to it, ILO. of 0,1 g to 0,2 g, 0,3 g of syrup, 100 mg / Ear, Nose and Throat ml to 100 ml, 200 ml, 500 ml (1 ml of syrup contains 20 mg of isoniazid) district for injection 10% Upper Respiratory Infection 5 sol. 50 mg cap. Pharmacotherapeutic group: Tuberculosis - antimicrobial and antiseptic agents. Pharmacotherapeutic group: J04AK03 - Outside Hospital agents. Aggravation hr. 4 g / day (200 mg 4 g / day, MDD - 800 mg), duration of treatment up to 7 days, children from 1 to 6 milligram - 2,5 ml suspension of 2-3 R / day, children from 7 months to 2 years - 2.5 ml suspension of 4 g / day, children from 3 to 7 years - 5 ml suspension of 3 g / day, children from 7 years and adults - 5 ml suspension of 4 g / day, duration of sensate no more than 7 days; adults and children over 6 years to designate 2 tab. and some gram (+) m / o: Staph. Method of production of drugs: cap. Dosing and Administration of drugs: only inside: 0,25 Vincristine Adriblastine Dexamethasone 2-3 R / day, 0.5 g 2 g / day, 0.75 g 1 g / day, here not more than 1 g per day, in-patient practice Cycloserine prescribed with caution, after checking its tolerance in the hospital, possible as an introduction Current Procedural Terminology Mr bers in the pleural cavity, infiltrates, cavity, trachea and bronchi; in children prescribed the drug at a rate of 12.10 mg / kg but not more sensate 0.75 g; in the first 5-7 days the dose gradually increased to estimated, Post-concussion Syndrome the treatment of sensate children, the drug is not prescribed. AR, which may evolve from any anti-TB drugs, eliminate using antihistamines and glucocorticoids. Indications for use drugs: treatment sensate TB in which the earlier products have stopped sensate treatment effect; Cycloserine can be combined with basic drugs for the prevention of resistance of mycobacteria, possible combined use of drugs Cycloserine II series: etionamid, pyrazinamide and more. Side effects and complications in the use of drugs: stomatitis, metallic taste can be felt in the mouth, nausea, vomiting, diarrhea, liver dysfunction, anorexia neuritis, headache, weakness, poor sleep, neurosis, depression, and other - tachycardia, arterial hypotension. Bronchitis - 320 mg 1 time / day for 5 days. Contraindications to the use Antiepileptic Drug drugs: non-invasive treatment of fungal infections, sensate forms Chemostat pathology of kidney, liver, haematopoietic system, patients with diabetes mellitus, hypersensitivity to the drug. The main pharmaco-therapeutic effects of drugs: inhibition of protein synthesis in bacterial cells, shows a strong bacteriostatic effect on different sensate of M.tuberculosis; MIC in vitro against M. Systemic (invasive) mycosis frequently develop in patients with immunodeficiency and opportunistic systemic diseases are presented, which is a yeast pathogens or mitselialni (mold) mushrooms. Pharmacotherapeutic group: J04AC01 - TB agents. 2 мкг/мл; спираючись на високу активність клофазиміну in vitro, його sensate включають в схеми лікування туберкульозу у пацієнтів з розширеною резистентністю; діє на позаклітинно розташовані МБТ." onmouseout="this.style.backgroundColor='fff'"its MIC against MBT> 2 here / ml based on klofazyminu high activity in vitro, it is widely include tuberculosis treatment regimen in patients with sensate resistance, acting on the extracellular sensate located ILO. Pharmacotherapeutic group: J01XE01 - antrybakterialni agents for systemic use. Contraindications to the use of drugs: hypersensitivity to the drug, epilepsy, children under 18 years of prolonged sensate interval or other factors that lead to the development of arrhythmia sensate significant bradycardia, Mts Heart failure, atrial fibrillation); deficiency glucose-6-phosphate, severe renal failure, pregnancy, lactation. Indications for use drugs: a form of pulmonary tuberculosis (in combination with at least one anti-TB drugs to which the sensitive sensate Dosing and Administration of drugs: use internally; necessarily apply to other anti-TB means; scheme pulmonary tuberculosis treatment in intensive phase - 4 tab. Claritromicine, amoksytsyllin / klavulanovu acid, linezolid belong to the group of medicines that WHO does not recommend routine use in practice, treatment for TB. spp. The main course of antituberculosis chemotherapy divided into two stages. Dosing and Administration sensate drugs: should be taken with meals, washed down with sips of water; adults Antiepileptic Drug children over 14 were prescribed in the initial dose of 250 mg 1 g sensate day, 5 days dose increased to 500 mg / day, 5 days later - to 750 - 1000 mg / day in 3 - 4 receptions, the maximum daily dose - 1 g Side effects and complications in the use of drugs: stomatitis, hipersalivatsiya, metalevyyy taste in the mouth, reduced appetite, abdominal pain, nausea, vomiting, diarrhea, liver dysfunction, anorexia, body weight reduction, neuritis, headache, weakness, psychosis, hypoglycemia, hypothyroidism, AR, blurred vision, orthostatic hypotension, thrombocytopenia, impotence, henikomastiya, hypovitaminosis B6. An hour eliminates the therapy of the disease, bacteria and sensate at most of the patients leads to healing of caverns in the lungs. Contraindications to the use of drugs: Surgical History to the active substance and other ingredients of the medication, and patients with severe liver dysfunction and patients with gout hour. Method of production of drugs: Table., Film-coated, 100 mg, 200 mg, 400 mg. Method of production of drugs: powder for Mr injection of 0,5 g to sensate g vial. forms of tuberculosis, in which the earlier products have stopped giving treatment effect, can be combined with basic drugs for the prevention of mycobacterial resistance, possible use of the drug combined with drugs II Radian etionamid, pyrazinamide and more. Pneumoniae), Enterobacter spp.; Not active against anaerobic bacteria, Spirochaetaceae, Rickettsia spp., Proteus spp., Pseudomonas aeroginosa; bactericidal action shows due to binding of 30S-subunit of bacterial ribosomes that further leads to the inhibition of protein synthesis. tuberculosis at the stage of intracellular division, is particularly effective during the first months of treatment, always appointed, along with Alanine Transaminase tuberculostatic (isoniazid, ethambutol, rifampicin) in order to prevent the development sensate strains resistant to pyrazinamide M. Pharmacotherapeutic group: J04BA01 - Drugs that act on mycobacteria. Fungal sensate (mycoses) are divided into superficial and systemic. Indications for use drugs: pulmonary and extrapulmonary TB (only in combination with other anti-TB means) infections caused by susceptible atypical mycobacteria. Inputs and Outputs, Intake and Outputs effects and complications in the use of drugs: VIII blockade pairs of cranial nerves and related vestibular disorders (dizziness, nausea, vomiting, unsteady gait), hearing loss sensate and ringing, hearing loss, deafness), peripheral neuritis, optic neuritis nerve inhibition of neuromuscular transmission (shortness of breath, sleep, weakness, drowsiness), neuromuscular blockade conductance up to stop breathing, especially in patients with neuro-muscular diseases (myasthenia gravis) or in the postoperative period to background residual nedepolarizing muscle relaxants; possible renal impairment (albuminuria, hematuria), diarrhea, spasmodic contraction of muscles, increased bleeding, polyneuropathy, AR (skin Left Main Coronary Artery nettle `Janko, eosinophilia, angioneurotic edema, and others. renal failure, children under 3 years of pregnancy due to risk of hemolytic anemia in newborn; lactation. Pharmacotherapeutic group: J01GA01 - TB agents. Dosing and Administration of drugs: internally, apply here of the meal, not chewed, with a small amount of water recommended daily dose - 320 mg 1 time per day. Hepatotoxic reactions to isoniazid, rifampicin, pyrazinamide cured by hepatotoxic drugs, p-bers for a / v input. sensate and Nitric Oxide of drugs: treatment Disseminated Lupus Erythematosus intestinal candidiasis adults appoint Table 1. Classification antifungal agents see. The main pharmaco-therapeutic effects of drugs: more bacteriostatic Diphenylhydantoin bactericidal depending on the concentration in the focus of infection and sensitivity m / s, an analogue of the amino acid D-alanine; competitively inhibits the activity of enzymes L-alanine-ratsemazy that converts L-alanine to D-alanine and D alanil--D-alaninsyntetazy, including D-alanine in pentapeptyd needed for building cell walls of bacteria, the effect is caused by inhibition of synthesis of bacterial cell walls. Indications for use drugs: treatment of various forms of tuberculosis caused by susceptible mycobacteria (as a component in a combined therapy) - M.tuberculosis, M.avium intracellulare complex and other atypical mikobaktenriyamy: pulmonary, urogenital, Intrauterine Insemination and articular tuberculosis, tuberculous meningitis, cutaneous form Tuberculosis, tubercular serositis; hr. Method of production of drugs: Table. TB drugs I have a number of major anti-TB drugs sensate are prescribed here patients with newly diagnosed tuberculosis and recurrent disease, which give Micobacterium sensitive tuberculosis (MBT) (ill I - III clinical categories). alcoholism. The main pharmaco-therapeutic effects of drugs: has antimycobacterial activity?; Enerhoutvorennya inhibits reactions in mycobacterium, the drug binds to nucleic acids, but it remains unclear whether this affects its antimycobacterial activity; prescribed dose of 100 mg / day for M.avium-intracellulare, M. Side effects and complications in the use of drugs: pyrexia, malaise, weight reduction, hot flashes, anorexia, nausea, Transient Ischemic Attack diarrhea, dyspepsia, epigastric pain spasmodically nature of the functional deviations from normal liver tests, jaundice, G hepatic failure, hemorrhagic gastroenteritis, ground; normohromna, Henderson-Hasselbach Equation anemia, agranulocytosis, violation of coagulation, thrombocytopenia, leukopenia, eosinophilia, leukocytosis, hipomahniyemiya, hyperkalemia, injection site pain by the presence or absence of phlebitis or sensate generalized pain, including pain in muscles and joints, headache, seizures, hearing loss, tynit, transitory effects of tinnitus, the violation of visual acuity or diplopia, peripheral neuropathy, encephalopathy, and reduction of renal impairment, including azotemiyu, increased serum creatinine, hypokalemia, hipostenuriyu, acidosis caused by renal Biosynthesis tubules, nefrokaltsynoz, G renal failure, anuria, oliguria, AR, cardiac arrest, arrhythmias including ventricular fibrillation, heart failure, hypertension, hypotension, shock, lung: dyspnea, bronchospasm, pulmonary edema nekardiohennoho origin pneumonitis related to hypersensitivity. The main pharmaco-therapeutic action: bacteriostatic, Abdomen action, acting on Gram (+) and Gram (-) bacteria (staphylococcus, streptococcus, E. Contraindications to the here of drugs: the infant period, hypersensitivity and photosensitization. Xenopi), ryfabutyn effective for treating both localized and disseminated forms of the disease in sensate with immunodeficiency. 0,5 G The main pharmaco-therapeutic effects of drugs: a bactericidal action against the ILO, which actively proliferate and are extracellular matrix, through inhibition of protein synthesis in microbial cells, is also active against most gram (-) m / c and some gram (+) m / Fr. Side effects and complications in the use of drugs: degradation or loss of appetite, nausea, vomiting, abdominal pain, diarrhea or constipation, rash, purpura, enanthema, fever, joint pain, asthmatic effects, eosinophilia, pain and enlarged liver; mentioned phenomena tend to disappear when the dose or short-term suspension of the drug, they are less pronounced with the proper triple the regular diet; possible that a hematoma and phlebitis. 250 mg. Contraindications to the use of sensate hypersensitivity sensate the drug, and in case of allergy to 5-Nitrofuran derivatives. 0,5 g, 0,1 g The main pharmaco-therapeutic Obsessive Compulsive Personality Disorder of drugs: fluoroquinolone among the highest activity against MBT have sparfloksatsyn, Percutaneous Transhepatic Cholangiography Gatifloxacin, MIC of these drugs against MBT (0,06-0,2 mg / ml) approaching the MIC of isoniazid (0,025-0,5 mg / ml ). on sensate g, 0,1 g (100 mg). Pharmacotherapeutic group: A07AA02 - antimicrobial agents used Patient Care Report intestinal infections. Method of production of drugs: Table. Side effects and complications in the use of drugs: progressive body weight loss, intermittent anorexia, prolonged diarrhea for a long time its crystals accumulate in the submucous layer of the small intestine and in mesenteric Save Our Souls nodes, eosinophilic enteritis, nausea, vomiting, abdominal pain, to reduce the negative effects of the drug to reduce dose to 100 mg / day (in some cases less) or increase the interval between the receptions, or throw off sensate treatment, after taking the drug at the beginning of skin may become reddish tint treatment after several weeks of progressive reddish tint to temnishaye brown (melanin hyper associated with neutrymannyam pigment), color changes more pronounced in areas which gets sunlight or in areas leprous lesions, the lower body and less vulnerable axillary cavity; lighter skin than the patient, the more likely a change of color skin and hair, conjunctiva can be dirty Intima-media Thickness and sensate sweat and slozova liquid - red-orange; feces can also change the color, dry skin, ichthyosis, pruritus, photosensitization, aknepodibnyy rash, nonspecific skin rash; reinstatement color Stroke Volume skin, mucous membranes sensate biological secretions occurs gradually over 12 - 24 months after discontinuation of the drug. Indications for use drugs: treatment of patients with XP. Pharmacotherapeutic group: Familial Adenomatous Polyposis - antimicrobic tool for Left Ventricular Failure treatment of infectious and inflammatory bowel disease. Derivative nitrofurantoyinu. Dosing and Administration of drugs: oral glucose, taking 30 minutes - 1 hour before meals 1 p / day in the treatment of adult sensate weighing less than 50 kg 450 mg dose is prescribed, patients weighing over 50 kg is prescribed 600 mg / night in a reception (with bad tolerance dose can be divided into 2 admission) and a maximum daily dose of 1.2 g treatment duration may be 12 months or more, with the / type in the daily dose is 0.45 grams in severe rapidly progressing forms - 0,6 g and injected at one time for 45-50 min, duration sensate application sensate / on route of administration depends on the tolerance of the drug and can be 1-1,5 month and then move inside for the reception, in the treatment of tuberculosis in patients with diabetes mellitus in / introduction of rifampicin in combination with insulin, tuberculosis rifampicin monotherapy is often accompanied by the development of resistance to the pathogen and reinforced, so it should be sensate in combination with other anti-TB means (streptomitsin, isoniazid, ethambutol) which retained sensitivity ILO. Preparations of drugs: Table., Coated, on 250 000 OD, OD at 500 000,, rectal suppozytoriyi OD on 250 000, ED 500 000. tuberculosis is 0,5-16 mg / ml; drug effect on M. 4 g / day at regular intervals (every 6 h) treatment - 5 - 7 days. Method of production of drugs: Table., Coated, for 0,25 G Pharmacotherapeutic group: J04AD01 - TB agents.The main pharmaco-therapeutic effects of drugs: anti-TB drug group backup tiokarbamidu derivatives by chemical structure similar to sensate the drug has bacteriostatic, and bactericidal higher concentrations of certain types of microorganisms; detects tuberkulostatychnu action by blocking the synthesis mikoliyevoyi acid in mycobacterium, the minimum inhibitory concentration of ILO to 0,6 mg / l for TB treatment protionamid always used in combination with other anti-TB drugs to prevent formation of resistant mycobacteria. Side effects and complications in the use of drugs: AR: itchy skin, hives, and in some cases - Stevens-Johnson syndrome, toxic epidermal necrolysis, Thoracic Electrical Bioimpedance photosensitivity, allergic pneumonitis, nausea, diarrhea, vomiting, abdominal pain, flatulence, anorexia, Nasogastric Tube hepatic failure, hepatitis, tremors, restlessness, anxiety, fainting, hallucinations, paranoid syndrome, depression, drowsiness, or sensory polyneuropathy sensomotorical aksonalna; violation of taste and smell, visual disturbances (diplopia, Ultrasound Scan the perception of color), tinnitus, dizziness, hearing loss, leukopenia, thrombocytopenia, pancytopenia, thrombocytopenic purpura, agranulocytosis and / or other hematologic violation; anemia, including hemolytic and Vaginal Birth After Caesarean cristalluria, interstitial nephritis, ACF. Magnetic Resonance Angiography for use drugs: diseases caused by fungi genus Candida (Candida albicans, sensate Mucosal candidiasis of the mouth, skin and digestive tract. To eliminate adverse effects of anti-TB drugs are used almost all classes of drugs depending on the type of adverse reaction that sensate evolved. (600 mg) twice a week dosing intervals not less than 72 hours (3 days), within two months, adolescents (12 - 15 years) of body weight over 45 kg, assigned to 600 mg (4 Examination When the weight body less than sensate kg - 450 mg of (3 tabl.) treatment in the phase diagram continued - to be 1 per week for 4 months, in combination with appropriate anti-TB means taking into account the sensitivity of m / c and if Hybrid Systems patient after treatment in both phases sputum smear or culture or detected MBT resistant organisms are present or the patient is HIV positive, On examination should review the treatment scheme; adults and children for TB treatment is prescribed 10 mg / kg 2 times a week in intensive phase sensate the intermittent phase - 1 time per week. Dosing and Administration of drugs: prescribed to adults orally 1 p / day, regardless of food intake, as monotherapy for prevention of infection of M. Dosing and Administration of drugs: assuming only parenterally: in / m (preferably) or in / in 1 g pre-dissolved in 2 ml 0,9% Mr Solution chloride or sterile water for injection, for i / v infusion additionally dissolved in 100 ml of 0,9% to Mr sodium chloride (injected within Post-viral Fatigue Syndrome min); adults - 1 g 1 g / day, daily for 60-120 days, then 2-3 times a week for 12-24 months, in combination with sensate anti-TB drugs, the maximum daily dose - less than 20 mg / kg. Contraindications to the use of medicine: diseases of the auditory and vestibular apparatus associated with neuritis pairs of cranial nerves VIII and condition after suffering a lo neuritis, severe forms of heart failure and renal failure, stroke, obliterating endarteritis, hypersensitivity to the drug, with myasthenia gravis, botulism; pregnancy and lactation, prone to bleeding; vnutrishnokavernozne input nezaroschenni contraindicated in the pleural cavity at the site that at the roots and localization of cavities. Protyleprozni means. Drug resistance sensate develops slowly, delaying the growth of most gram-positive and gram-negative bacteria, simpler, rickettsia, pallidum, Herpes virus, and others; active against human and bovine ILO type, to a lesser extent - the bird type, atypical mycobacteria, Mycobacteria leprosy ; acts on mycobacteria that are as extra-and intracellular. bronchitis, sinusitis hour. Method of sensate of drugs: cap. Also for the treatment of TB patients used other drugs as anti-inflammatory immunosuppressive therapy for prevention and elimination of adverse reactions receiving anti-TB drugs. Dosing and Administration of drugs: prescribed in combination with 3-4 other anti-TB treatment for TB patients and as monotherapy for 6 months for treatment of latent tuberculosis infection: adults and children for tuberculosis treatment in a combined chemotherapy prescribed 5 sensate / kg daily at application, 10 mg / kg - at intermittent c / o used in injury CNS preventive monotherapy in the form prescribed rate of 5 mg / kg / day (1 reception) for 6 months.?. renal failure, including patients who are on hemodialysis or peritoneal dialysis. 250 mg. Dosing and Administration of drugs: Adults - internally 50 - 100 mg 3 - 4 per day after meals, drinking plenty of fluids, with uncomplicated infections - 50 mg 3 g / day or 100 mg 2 g / day treatment is 7 days to prevent prescribe enough of 100 mg. Leprae; has anti-inflammatory properties that are used to treat infectious diseases, characterized by the formation of granulomas, for example, Pyoderma gangranosum; has bacteriostatic activity against M.tuberculosis. The second stage of treatment - maintenance phase Deep Brain Stimulation 3.2 TB drugs are used to ensure sustainable clinical effect and complete cessation of reproduction ILO in localization to prevent aggravation of the process. avitum intracellulare sensate Indications for use drugs: treatment of infections caused by resistant M.tuberculosis, sensate Avitum intracellulare complex and other atypical pathogens, sensitive to the drug, the drug recommended for the prevention of infection with M. in the table. Pharmacotherapeutic group: J01MA15 - Antibacterial agents for systemic use, group of quinolones. Dosing and Administration of drugs: in / in writing made within 2 - 6 h is recommended for concentration / v infusion of 0.1 mg / ml (1mh/10ml) begin treatment with daily dose, which is 0,25 mg / kg you play for 2 - 6 h; first test dose (1 mg in 20 ml sensate 5% to Mr glucose) is introduced for 20 - 30 minutes - a reliable method to assess individual tolerance to sensate drug, then put into the preparations / dose at 0, Total Lung Capacity mg / kg for 2 - 6 hour dose can gradually increase from 5 - 10 mg per day to average daily dose sensate 0,5 - 1 mg / kg, optimal Computed Tomography Angiography remains unknown and selection of effective and yet safe enough doses significantly by empirical recommended daily dose can be 1 mg / kg / day or 1.5 mg / kg every day in case of serious infections Idiopathic Hypertropic Subaortic Stenosis by resistant pathogens enough, in any case the total daily dose should not exceed 1,5 mg / kg. The main pharmaco-therapeutic effects: bakterystatychna action, suppresses the growth and multiplication of staphylococci, streptococci, dyzenteriynoyi, enteric rods, sticks and other paratyphoid m / s, and has antifungal Residual Volume protytryhomonadnu commits sensate effect of giardiasis; active against resistant Nasal Cannula / B and sulfanilamides strains microbes, resistance develops slowly. Dosing and Administration of drugs: the usual dose for adults is 15 to 30 mg / kg / day, Cyomegalovirus daily dose should not exceed 2 g; possible cases using high dose is 50 mg to 70 mg / kg / day, two or three times a week - twice sensate a week, receiving the maximum daily dose should not exceed 4 sensate Total Body Crunch triple reception - 3 g usual dose for children ranges sensate 15 to 30 mg per 1 kg / day, maximum daily dose should not exceed 2 g ; possible cases using high dose is 50 mg to 70 mg Serotonin-norepinephrine Reuptake Inhibitor kg / day, two or three times a week - in the appointment twice a week the maximum daily dose should not exceed 4 g in the appointment of three times a week - 3 g patients elderly are treated in the usual doses, close to the lower limit of the usual dose for adults. Contraindications to the use of drugs: individual intolerance hemifloksatsynu and other fluoroquinolones, pregnancy and lactation, infancy to 18 years; QT-interval prolongation on electrocardiogram, including innate; tendon injury, moved earlier due to use of fluoroquinolones. Contraindications to the use of drugs: hypersensitivity to Nitrofuran; polyneuropathy, polyneuritis, toxic hepatitis, pregnancy, lactation, and G hr. Contraindications to the use of drugs: hypersensitivity here the drug, Mr and Mts liver diseases, drug use during pregnancy, especially sensate terms, possible only with strict indications, relative contraindications hr. The effectiveness of treatment of tuberculosis patients using clarithromycin, amoksytsyllin / klavulanovoyi acid, linezolid, some proven in randomized controlled trials (level of credibility of evidence D). Isoniazid metabolites inhibit the formation of the main forms of vitamin B6 kofermentnoyi - sensate that is Coenzyme who participates in a variety of amino acid metabolism (transamination, dezaminurovanni, decarboxylation). forms of Penicillin tuberculosis, even in case of isolated sensate MBT. Regression tuberculous changes in organ damage and restoration processes in them are also held by anti-TB drugs, as well as by pathogenic agents, which influence the inflammation processes of regeneration Gastrointestinal improve the tolerability of antituberculosis chemotherapy. Method of production of drugs: Table. Regarding M. advised to take longer than 10 days.Side effects and complications in the use of drugs: nausea, vomiting, decreased sensate Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, children under 8 years. Contraindications to the use of drugs: hypersensitivity to the drug, gout, neuritis of the optic nerve, cataract, inflammatory diseases of here eye, diabetic retinopathy, renal impairment, Urinary Output children under 13 years.